Siren is typically used in consort with a number of other packages; for more information, see the links below
CSL: the CREATE Signal Library: a C++ framework for building OSC-controllable synthesis/processing servers
http://create.ucsb.edu/CSL
Loris: a sound analysis/resynthesis package written by Kelly Fitz
http://sourceforge.net/projects/loris
SuperCollider: an efficient synthesis and processing language very similar to Smalltalk
http://supercollider.sourceforge.net/
CRAM: the CREATE Real-time Applications Manager: a tool for describing and managing complex distributed real-time software systems
http://create.ucsb.edu/CRAM
Occam: An OSC-to-MIDI translator
http://www.mat.ucsb.edu/~c.ramakr/illposed/occam.html
Macco: a MIDI-to-OSC convertor
http://www.create.ucsb.edu/CSL/Macco.zip
FMAK: the FASTLab Music analysis Kernel (a sibling of CSL)
http://fastlabinc.com/
libSndFile: http://www.mega-nerd.com/libsndfile
PortMidi: http://www.cs.cmu.edu/~music/portmusic
PortAudio: http://www.portaudio.com
FFTW: the fastest FFT in the west
http://www.fftw.org